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List of Projects 2022/23

01. Monica Canepari

Exercise performance and gender differences – the role of individual muscle fibers properties

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02. Ornella Cazzalini

Studying interactions between proteins involved in cell cycle regulation and DNA replication and repair

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03. Lia Crotti

Novel pharmacological strategies for the treatment of the Long QT Syndrome

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04. Antonio di Sabatino

Inflammation and Cancer: histologic and molecular studies of precancerous changes in coeliac and Crohn’s disease

05. Christina Kiel

Computational energy supply and demand model of the aging human outer retina

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06. Umberto Laforenza

Aquaporins in tumor cells: regulatory mechanisms from intracellular to nanotubes and microvesicles passing through the plasma membrane

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07. Konstantinos Lefkimmiatis

Title of the research project: Unravelling the code of mitochondrial-nuclear communication

08. Marco Lolicato and Cristina Arigoni

The KCC2 interactome: A structural approach to provide mechanistic understanding of GABAergic inhibition and therapeutic venues for neurodevelopmental disorders

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09. Mario Mondelli

A multidisciplinary approach to identify biomarkers of Post-Acute Sequelae of SARS-CoV-2 infection

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10. Mario Nuvolone

Dissecting the pathogenic role of N-glycosylation in AL amyloidosis: molecular bases, diagnosis, and treatment

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11. Carla Olivieri

Cryptic Pathogenic Variants in Hereditary Haemorrhagic Telangiectasia: a Whole Genome Sequencing approach

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12. Arianna Palladini

Vaccines to overcome Therapeutic Resistance in Lung Cancer

13. Giovanni Palladini

Promoting Diagnosis and management of AL in Italy

14. Maria Antonietta Pellegrino

Fibro-adipogenic precursors (FAPs): novel players in muscle plasticity

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15. Roberto Pizzala and Paola Perin

Neurogenesis, immunity, and inflammation in the auditory system

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16. Monica Savio

Cellular and molecular mechanisms of resveratrol derivatives against cancer development

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17. Claudia Scotti

Structural basis of antibody affinity maturation

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18. Virginie Sottile

Developing cancer stem cell differentiation models using 3D organoids to potentiate oncotherapies

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19. Enza Maria Valente

Functional characterization of a novel gene implicated in neurodevelopment

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20. Enza Maria Valente

Characterization of a novel mitochondrial function of PINK1 in Parkinson disease pathogenesis|

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21. Alessandra Balduini

Bone marrow modeling for platelet production

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22. Christian di Buduo

Calcium signaling networks in physiological and pathological megakaryopoiesis

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23. Massimiliano Gnecchi

Use of induced pluripotent stem cells for the study of ion channel heart disease

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24. Marco Lolicato

Development of miniaturized technologies for the development and electrophysiological validation of novel molecules on ion channels and transporters involved in orphan cancer or neurodevelopmental disorders

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25. Virginie Sottile

Development of 2D & 3D culture models of neurogenesis using patient-derived stem cells to study neurodevelopmental diseases

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