List of Projects 2023/24

Bone marrow modeling for platelet production

Calcium signaling networks in physiological and pathological megakaryopoiesis

A multidimensional assessment for tackling malnutrition in inflammatory bowel disease: IBD-onfoods

Pathogenic mechanisms and therapeutic strategies in Autosomal Dominant adult-onset LeukoDystrophy (ADLD)

Classification of variants of unknown/uncertain significance (VUS) for the long QT syndrome by using patient-specific iPSCs-derived cardiomyocytes (iPSC-CMs)

Analysis of cell network rewiring in the aging human outer retina

Aquaporins in tumor cells: regulatory mechanisms from intracellular to nanotubes and mi-crovesicles passing through the plasma membrane.

Investigating the transcriptional regulation of Mitochondria-related nuclear genes

FIBROmeltIN: TARGETING FIBRONECTIN IN MYELOFIBROSIS

Genetic and clinical heterogeneity in Shwachman-Diamond Syndrome

Patients-specific M protein sequences as a key to study and track B cell / plasma cell tumors.

Development of cancer vaccines against plasticity antigens to overcome therapeutic resistance in lung cancer

Fibro-adipogenic precursors (FAPs): novel players in muscle plasticity.

Impact of exercise and disuse on healthy aging: a translational approach to define neuromuscular changes according to sex-related differences

Radiation therapy and asparaginase: building a new approach for a combined cancer therapy

Idiopathic polyhydramnios: an understated indicator of genetic and neuropsychiatric conditions?

3D spheroid cancer models to develop treatments targeting tumour stem cell and potentiate oncotherapies.

Therapeutic approach against the novel molecular target SerpinB3 for glioblastoma

Sculpting the GAS6 LG1 domain to inhibit/enhance AXL activity

Nanotechnology applications for innovative therapeutic approaches