The Department of Molecular Medicine is pleased to invite you to participate to the seminar of Dr. Felice-Alessio Bava (Stanford University / INSERM), entitled:

"From fundamental questions to technology development, and back: a focus on in situ transcriptomics and cancer".

The seminar will take place in the Aula Mosca, via Forlanini 14/16, starting from 12pm on Friday 9 February 2024.

Biosketch:

Dr. Bava worked in the laboratory of Prof. Garry Nolan, where he carried out studies in the field of cancer/cancer immunology (Nat. Commun., 2023) and co-developed multiple single-cell and spatial technologies (Nat. Methods 2016, Science 2018, Commun. Biol. 2020, Nat. Commun. 2021). After a brief experience as Principal Investigator at Institut Curie, he decided to join 10x Genomics where he started a team to develop an "in situ transcriptomics" method, recently commercialized under the name of Xenium.
In his seminar, he will discuss how fundamental questions in the field of RNA biology fueled the need of developing new methods that enable co-detection of proteins and RNAs in single-cells by mass-cytometry, and how a sequencer can be used as if it were a cytometer. He will then share how a fundamental question in the field of cancer immunology led him to develop (i) a method for super-resolution imaging of subcellular structures and (ii) “STARmap” an in situ transcriptomics method that enables visualization of 1000s of RNAs in thick tissues. Finally, he will describe what it takes to bring in situ transcriptomics to industry, so that many labs in the world would be able to use it, showcasing its usefulness in the study of tumor-microenvironment.

The Mondino Foundation, the University of Pavia and the Collegio F.lli Cairoli announce the first edition of the "Pavia meets..." event.

In this first edition, Prof. Katrin Brockmann, Dr. Julia Fitzgerald and Prof. Thomas Gasser from the University of Tübingen and the Hertie Institute for Clinical Brain Research in Tübingen will talk about clinical and research developments on Parkinson's disease.

The introduction of the conference will be handled by Prof. Enza Maria Valente and Dr. Micol Avenali.

For more information, see the attached PDF file.

The Department of Molecular Medicine is pleased to invite you to the seminar of Dr. Marilena Crescente (Lecturer of Haematology - Manchester Metropolitan University), entitled:

Platelets in fungal infection: protective or detrimental role?

The seminar will take place in Room A at the Golgi-Spallanzani Institute (second floor, Pharmacology section), at 3 pm on 30 January 2024.

For more information alessandra.balduini@unipv.it

The Department of Molecular Medicine is pleased to invite you to the seminar of Prof. Chris Sundberg (Michigan State University), entitled:

PHYSIOLOGICAL PROCESSES THAT LIMIT HUMAN NEUROMUSCULAR PERFORMANCE IN HEALTH, AGING, AND DISEASE.

The seminar will take place on January 15, 2024, in Room A of Human Physiology (via Forlanini, 6) starting at 3:00 pm.

Biosketch

Chris Sundberg earned both a Bachelor and Master of Science degree in Kinesiology from the University of Wyoming. In 2013, he started the pursuit of a Ph.D. in the Clinical and Translational Rehabilitation Health Science program at Marquette with Dr. Sandra Hunter. His dissertation work focused on identifying the mechanisms for the age-related increase in fatigability during dynamic exercise. Immediately following graduation, he began postdoctoral work studying cellular muscle physiology and energetics of aging human skeletal muscle with Dr. Robert Fitts in the Department of Biological Sciences. In 2020, Chris was hired as an Affiliate Faculty through the Athletic and Human Performance Research Center (AHPRC) and is an Assistant Professor of Exercise Science in the Department of Physical Therapy.

Dr. Sundberg’s research focuses on identifying the etiologies of muscle fatigue and the physiological processes that limit human neuromuscular performance in health, aging, and disease. His lab adopts an integrative and translational approach employing multiple cutting-edge techniques to study fatigue and the limits of human performance in the whole limb down to the cellular and molecular levels. He also investigates the adaptive response to exercise training with the goal of developing targeted exercise interventions to improve muscle power output and fatigability in both healthy and clinical populations. Dr. Sundberg’s research has been supported by the National Science Foundation (NSF), National Aeronautics and Space Administration (NASA), American Hearth Association (AHA), and the National Institutes of Health (NIH).

The Department of Molecular Medicine is pleased to invite you to the lecture of  Monica Giannotta,  PhD (Postdoc at the San Raffaele Scientific Institute, Milan) entitled:

Dual role of brain endothelial Gpr126 in blood-brain barrier development and ischemic stroke

The seminar will take place online on Thursady July 6 (https://us02web.zoom.us/j/7380019712), from 12 a.m.

For further information, take a look at the attached PDF file, or write to Prof. R. Bottinelli Prof. R. Bottinelli (roberto.bottinelli@unipv.it).

The Department of Molecular Medicine is pleased to invite you to the lecture of Alberto Malerba (Gene Medicine Laboratory for Rare Diseases, Dept. Biological Sciences, Royal Holloway, University of London, UK) inititolato:

"Gene therapy and antisense therapeutics for the treatment of neuromuscular diseases”

The seminar will take place online on Thursady June 29 (https://us02web.zoom.us/j/7380019712), from 4 p.m.

For further information, take a look at the attached PDF file, or write to Prof. R. Bottinelli Prof. R. Bottinelli (roberto.bottinelli@unipv.it).

The Department of Molecular Medicine is pleased to invite you to the seminar of Nasrollah Rezaei-Ghaleh, MD PhD (DFG Research Group Leader Institute of Physical Biology Heinrich Heine University - HHU, Dusseldorf, Germany), entitled:

"Functional dynamics of neurodegeneration-related disordered proteins viewed through the lens of nuclear spin"

The seminar will take place online on June 28 (https://us02web.zoom.us/j/7380019712), from 4 p.m.

For further information, take a look at the attached PDF file, or write to Prof. R. Bottinelli Prof. R. Bottinelli (roberto.bottinelli@unipv.it)